NMN products that contain other ingredients, such as vitamins, minerals, herbs, and other substances, may cause side effects in some people. It’s essential to always read supplement labels to learn exactly what you’re ingesting
NMN how to use for body
NMN is the main precursors of NAD
NMN is the main precursors of NAD+ — an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival. Impressive results in cell and animal studies, as well as in clinical trials, are fuelling a multimillion-dollar market for NMN supplements.“In rodents, NMN ameliorates the detrimental effects of NAD+ reduction with age, and it significantly improves several metabolic functions,” says Samuel Klein, a doctor and nutritional specialist at Washington University School of Medicine in St Louis, United States. “This has led to NMN being sold worldwide as a diet supplement, with very little data to support that it has beneficial effects in people.”
NMN may support healthy aging,” says Piper. However, she also shares that most studies on NMN are in vitro or animal studies.
There is minimal clinical evidence on the potential benefits of NMN for humans. Thus, more human clinical trials are needed to confirm its benefits as a dietary supplement.
Meanwhile, researchers do know that as one of the primary precursors of NAD+ and intermediaries in NAD+ biosynthesis, NMN is as essential as NAD+ in the body’s proper functioning of cells.
NAD+ plays an important role in the following cellular functions (according to existing research):
- DNA repair
- Circadian rhythms
- Energy metabolism
- Stress resistance
Many commercial products containing NMN typically offer between 50 milligrams and 150 milligrams per capsule. There are also anti-aging and longevity supplements with higher NMN dosages, reaching up to 500 milligrams per dose.
NMN Side Effects
NMN is generally considered safe, and no major side effects have been reported in humans,” says Sabat. “[However], since NMN is a relatively new supplement, long-term safety data is limited, and it’s always advisable to consult with a health care professional before starting any new supplement.”
One small 2021 study in Frontiers in Nutrition observed 30 participants taking either 250 milligrams of NMN or a placebo daily for 12 weeks and concluded that NMN users may experience mild side effects including abdominal pain, diarrhea, gas and upper respiratory health issues
NMN May Boost NAD+ Levels
NMN Nicotinamide mononucleotide Limited research suggests supplementing with NMN could help increase NAD+ levels in certain populations.A recent study including 30 healthy adults found supplementation with 250 milligrams (mg) of NMN per day for 12 weeks significantly increased blood levels of NAD+ compared to placebo treatment