Ursolicacid (sometimes referred to as urson, prunol,malol, or 3-beta-3-hydroxy-urs-12-ene-28-oic-acid), is a pentacyclic triterpeneacid, used in cosmetics that is also capable of inhibiting various cancer celltypes by inhibiting the STAT3 activation pathway, one of which includes humanfibrosarcoma by reducing expression of matrix metalloproteinase-9 viaglucocorticoid receptors. It may also decrease proliferation of cancer cellsand induce apoptosis. Ursolic acid has also been shown to inhibit JNKexpression and IL-2 activation of JURKAT leukemic T Cells leading to thereduction in proliferation and T cell activation.
Ursolic acid can serve as a startingmaterial for synthesis of more potent bioactive derivatives, such as antitumoragents. It has been found to reduce muscle atrophy and to stimulate musclegrowth in mice. Ursolic acid has potential use as a cardioprotective compound.
Ursolic acid was found to be a weakaromatase inhibitor (IC50 = 32 μM).
Ursolic acid has been shown to increase theamount of muscle and brown fat and decrease white fat obesity and associatedconditions when added to diets fed to mice. Under physiological concentrations,ursolic acid also induces eryptosis (the apoptosis-like suicidal cell death indefective red blood cells).
| ITEMS | STANDARD |
| Part used | Fruit |
| Specification | 1%—10% PAC by BL-DMAC5%~50% Proanthocyanidin by UV |
| Appearance | deep violet fine powder |
| Flavor & Odor | Characteristic |
| Particle size | 100% pass 80 mesh |
| Loss on Drying | =<5.0% |
| Bulk density | 40-60g/100ml |
| Sulphated Ash | =<5.0% |
| GMO | Free |
| General Status | Non-irradiated |
| Pb | =<3mg/kg |
| As | =<1mg/kg |
| Hg | =<0.1mg/kg |
| Cd | =<1mg/kg |
| Proanthocyanidin | >=30% |
| Total microbacterial count | =<1000cfu/g |
| Yeast & Mold | =<100cfu/g |
| E.Coli | Negative |
1, What kinds of certificates can you offer?
Chems is an ISO2008 9001 certified company, as for Bearberry Extract - Ursolic Acid, we can offer HAPPC, KOSHER, HALAL Certificates, ect.
2, Is Chems a manufacturer or just a trading company?
Chems is both manufacturer and trading company, we are Bearberry Extract - Ursolic Acid distributor, at the same time, we are manufacturer of other products.
3, What is the Min Order Quantity of Bearberry Extract - Ursolic Acid?
Different products have different MOQ, for Bearberry Extract - Ursolic Acid, the MOQ is 500kg.
4, What is the price of Bearberry Extract - Ursolic Acid?
Chems is a famous supplier and manufacturer of Bearberry Extract - Ursolic Acid in China, and has been corporate with many Bearberry Extract - Ursolic Acid suppliers for several years, we can provide you with cost-effective Bearberry Extract - Ursolic Acid.
5, How long shall we wait for your reply?
We can guarantee to reply your inquiries of Bearberry Extract - Ursolic Acid in less than 24 hours in working days.
6, What kinds of transportation types can you provide?
Our main transportation methods include air transportation, land transportation and water transportation.
7, What kinds of payment terms can you accept?
The most commonly used payment terms are T/T, L/C, D/P, D/A, etc.
8, How long will I receive my good?
Chems has its own EDC warehouse in Shanghai, when your purchase order has been confirmed, inventory products will deliver within 1 week, other products delivery in 2 weeks.